汪世华，男，博士，二级教授，博导，十大网投官方入口科技处、社会科学处（合署）处长，福建省病原真菌与真菌毒素重点实验室主任，福建省重点学科和一流学科“生物学”一级学科博士点学科带头人，十大网投官方入口学术委员会秘书长。
现为国家百千万人才工程人选、有突出贡献中青年专家，享受国务院政府特殊津贴专家，全国模范教师，教育部新世纪优秀人才，获教育部霍英东青年教师奖。福建省特支人才“双百计划”百千万工程领军人才，福建省杰出青年基金，获福建省五一劳动奖章，福建青年五四奖章。
主要从事黄曲霉为代表的农业微生物和微生物毒素方面的研究，中国菌物学会常务理事、真菌毒素专业委员会主任，中国微生物学会理事、分析微生物专业委员会副主任，福建省生物工程学会理事长。
一、主持的科研项目
国家重点研发计划课题（2019YFC0312602），2020-2022，主持
国家重点研发计划课题（2017YFD0200601），2017-2020，子课题主持
国家自然科学基金面上项目（31972214），2020-2023，主持
国家自然科学基金面上项目（31772105），2018-2021，主持
福建省杰出青年基金滚动项目，2018-2020，主持
福建省海洋经济发展补助资金项目（FJHJF-L-2020-3），2020-2021，主持
国家863计划课题（2007AA10Z430），2007-2010，主持
国家973计划课题（2013CB127802），2013-2017，子课题主持
国家自然科学基金面上项目（31172297），2012-2012，主持
国家自然科学基金面上项目（30771400），2008-2010，主持
国家自然科学基金青年基金项目（30500325），2006-2008，主持
二、科技获奖
1) 福建省技术发明奖二等奖，排名第一，2014
2) 福建省自然科学奖二等奖，排名第一，2010
3) 福建省优秀学术论文一等奖，排名第一，2020
4) 福建省青年科技奖，个人，2011
5) 福建省运盛青年科技奖，个人，2011
三、专著及主编教材
1) 汪世华等编著．黄曲霉与黄曲霉毒素．科学出版社，2017;
2) 汪世华等编著．《抗体技术》（第二版）．科学出版社，2018;
3) 汪世华主编．《蛋白质工程》第二版．科学出版社，2017;
4) 汪世华主编．《分子生物学》．高等教育出版社，2011
四、综合荣誉
国家百千万人才工程人才人选、有突出贡献中青年专家，2019
享受国务院政府特殊津贴专家，2014
教育部新世纪优秀人才支持计划，2010；
全国模范教师，2014
教育部霍英东青年教师奖三等奖，2012
福建省政协第十一届、十二届委员会委员，2012
《Frontiers in Food Microbiology》编委（2013-）
《Toxins》编委（2021－）
五、学术论文代表作
1) Zhuo Zhu+, Gengli Ma+ Mingkun Yang, Can Tan, Guang Yang, Sen Wang, Na Li, Feng Ge, Shihua Wang*. Ras subfamily GTPases regulate development, aflatoxin biosynthesis and pathogenicity in the fungus Aspergillus flavus. Environmental Microbiology, 2021, 23(9): 5334-5348.
2) Guang Yang#, Yuewei Yue#, SilinRen#, Mingkun Yang#, Yi Zhang, Xiaohong Cao, Yinchun Wang, Jia Zhang, Feng Ge, Shihua Wang*. Lysine acetylation contributes todevelopment, aflatoxin biosynthesis and pathogenicity in Aspergillus flavus. Environmental Microbiology, 2019, 21 (12): 4792-4807.
3) Yu Wang#, Sen Wang#, Xinyi Nie, Kunlong Yang, Peng Xu, Xiuna Wang, Mengxin Liu, Yongshuai Yang, Zhuo Chen, Shihua Wang*. Molecular and structural basis of nucleoside diphosphate kinase–mediated regulation of spore and sclerotia development in the fungus Aspergillus flavus. Journal of Biological Chemistry, 2019, 294(33): 12415-12431.
4) Zhuo Zhu#, Mingkun Yang#, Youhuang Bai#, Feng Ge, Shihua Wang*. Antioxidant Related Catalase CTA1 Regulates Development, Aflatoxin Biosynthesis and Virulence in Pathogenic Fungus Aspergillus flavus. Environmental Microbiology, 2020, 22 (7): 2792-2810.
5) Xuan Chen#, Lianghuan Wu#, Huahui Lan#, Ruilin Sun, Meifang Wen, Danrui Ruan, Mengjuan Zhang, Shihua Wang*. Histone acetyltransferases MystA and MystB contribute to morphogenesis and aflatoxin biosynthesis by regulating acetylation in fungus Aspergillus flavus. Environmental Microbiology, 2021, 11. DOI: 10.1111/1462-2920.15856.
6) Mingkun Yang, Zhuo Zhu, Youhuang Bai, Zhenhong Zhuang, Feng Ge, Mingzhu Li, Shihua Wang*. A novel phosphoinositide kinase Fab1 regulates biosynthesis of pathogenic aflatoxin in Aspergillus flavus. Virulence, 2021, 12 (1): 96-113.
7) Can Tan†, Jili Deng†, Feng Zhang, Zhuo Zhu, Lijuan Yan, Mengjuan Zhang, Jun Yuan, Shihua Wang*. CWI pathway participated in vegetative growth and pathogenicity through a downstream effector AflRlm1 in Aspergillus flavus. iScience, 2021, 24 (10): 103159.
8) Silin Ren#,Mingkun Yang#,Yuewei Yue#, Feng Ge,Yu Li, Xiaodong Guo, Jia Zhang, Feng Zhang, Xinyi Nie, Shihua Wang*. Lysine Succinylation Contributes to Aflatoxin Production and Pathogenicity in Aspergillus flavus. Molecular & cellular proteomics, 2018, 17 (3): 457-471.
9) Guang Yang, Xiaohong Cao, Genli Ma, Ling Qin, Yuanzhen Wu, Jian Lin, Peng Ye, Jun Yuan, Shihua Wang*. MAPK pathway-related tyrosine phosphatases regulate development, secondary metabolism and pathogenicity in fungus Aspergillus flavus. Environmental Microbiology, 2020, 22 (12): 5232-5247.
10) Mingkun Yang, Zhuo Zhu, Zhenhong Zhuang, Youhuang Bai, Shihua Wang*, Feng Ge*. Proteogenomic characterization of the pathogenic fungus Aspergillus flavus reveals novel genes involved in aflatoxin production. Molecular and Cellular Proteomics, 2021, 20: 100013.
11) Rongzhi Wang#, Juncheng Wang#, Haimei Liu, Yehong Gao, Qiang Zhao, Sumei Ling, Shihua Wang*. Sensitive immunoassays based on specific monoclonal IgG for determination of bovine lactoferrin in cow milk samples. Food Chemistry, 2021, 338: 127820.
12) Peiyuan Cai, Rongzhi Wang, Sumei Ling, Shihua Wang*. A high sensitive platinum-modified colloidal gold immunoassay for tenuazonic acid detection based on monoclonal IgG. Food Chemistry, 2021, 360: 130021.
13) Sumei Ling#, Xiulan Li#, Qiang Zhao, Rongzhi Wang, Tao Tan, Shihua Wang*. Preparation of monoclonal antibody against penicillic acid (PA) and its application in the immunological detection. Food Chemistry, 2020, 319: 126505. https://doi.org/10.1016/j.foodchem.2020.126505.
14) Sumei Ling#, Qiang Zhao#, Muhammad Naeem Iqbal#, Mingke Dong, Xiulan Li, Ming Lin, Rongzhi Wang, Feiya Lei, Caizhen He, Shihua Wang*. Development of immunoassay methods based on monoclonal antibody and its application in the determination of Cadmium ion. Journal of Hazardous Materials, 2021, 411： 124992.
15) Feng Zhang#,Luhua Huang#,Jili Deng#,Can Tan,LongpoGeng, Yun Liao, Jun Yuan, Shihua Wang*. A cell wall integrity-related MAP kinase kinasekinase AflBck1 is required for growth and virulence in fungus Aspergillus flavus. Molecular Plant-Microbe Interactions, 2020, 33 (4): 680-692.
16) Huahui Lan, Lianghuan Wu, Ruilin Sun, Nancy P Keller, Kunlong Yang, Liuqing Ye, Shuibin He, Feng Zhang, Shihua Wang*. The HosA histone deacetylase associates with Sin3 to control aflatoxins biosynthesis through direct regulation of aflatoxin cluster genes. Molecular Plant-Microbe Interactions, 2019, 32 (9): 1210-1228.
17) Rongzhi Wang#,Yanfang Zhong#,Juncheng Wang,Hang Yang, Jun Yuan,and Shihua Wang*. Development of an ic-ELISA and immunochromatographic stripfor analysis and detection of ω-conotoxin MVIIA. Journal of Hazardous Materials, 2019, 378: 120510.
18) Kunlong Yang, Yana Shadkchan, Joanna Tannous, Julio Landero Figueroa, Philipp Wiemann, Nir Osherov, Shihua Wang*, Nancy P. Keller*. Contribution of ATPase copper transporters in animal but not plant virulence of the crossover pathogen Aspergillus flavus. Virulence, 2018, 9 (1): 1273-1286.
19) Sumei Ling, Qing-Ai Chen, Yuming Zhang, Rongzhi Wang, Ni Jin, Jie Pang, Shihua Wang*. Development of ELISA and Colloidal Gold Immunoassay for Tetrodotoxin Detetcion Based on the Monoclonal Antibody. Biosensors and Bioelectronics, 2015, 71, 256-260.
20) Rongzhi Wang, Linmao Zeng, Hang Yang, Yanfang Zhong, Juncheng Wang, Sumei Ling, Abdullah farhan Saeed, Jun Yuan, Shihua Wang*. Detection of Okadaic Acid (OA) using ELISA and Colloidal gold immunoassay based on monoclonal antibody. Journal of Hazardous Materials, 2017, 339: 154-100.
21) Jing Zhang, Xi Zhang, Guidi Yang, Jinghua Chen*,Shihua Wang*. A signal-on fluorescent aptasensor based on Tb3+ and structure switchingaptamer for label-free detection of Ochratoxin A in wheat. Biosensors and Bioelectronics, 2013，41: 704-709.
22) Bin Wang, Xiaoyun Han, Youhuang Bai, MengguangQiu, Feng Zhang, Zhenhong Zhuang, Jun Yuan, Xinyi Nie, Shihua Wang*. Effects of nitrogen metabolism on growth and aflatoxin biosynthesis in Aspergillus flavus. Journal of Hazardous Materials, 2016, 324: 691–700.
23) Zhenhong Zhuang*, Yaling Huang, Yanling Yang, Shihua Wang*. Identification of AFB1-interacting proteins and interactions between RPSA and AFB1. Journal of Hazardous Materials, 2016, 301: 297-303.
24) Jinghua Chen, Xi Zhang, Shuxian Cai, Dongzhi Wu, Mei Chen, Shihua Wang*, Jing Zhang*, A Fluorescent Aptasensor based on DNA Scaffolded Silver-Nanocluster for Ochratoxin A Detection, Biosensors and Bioelectronics, 2014，57：226-231
25) Kunlong Yang#, Yinghang Liu#, Sen Wang, Lianghuan Wu, Rui Xie, Huahui Lan, Opemipo Esther Fasoyin, Yu Wang, Shihua Wang*. The cyclase-associated protein Cap with multi-domain contributes to mycotoxin biosynthesis and fungal virulence in Aspergillus flavus. Journal of Agricultural and Food Chemistry, 2019, 67 (15): 4200-4213.
26) Rongzhi Wang, Xiaosong Gu,Zhenghong Zhuang, Yanfang Zhong, Hang Yang, Shihua Wang*. Screening and molecular evolution of a single chain variable fragment antibody (scFv) against Citreoviridin toxin. Journal of Agricultural and Food Chemistry, 2016, 64: 7640-7648.
27) Xinyi Nie, Song Yu, MengguangQiu, Xiuna Wang, Yu Wang, Youhuang Bai, Feng Zhang, Shihua Wang*. Aspergillus flavus SUMO Contributes to the Fungal Virulence and Toxin Attributes. Journal of Agricultural and Food Chemistry, 2016, 64: 6772-6782.
28) Rongzhi Wang, Xiaosong Gu,Zhenghong Zhuang, Yanfang Zhong, Hang Yang, Shihua Wang*. Screening and molecular evolution of a single chain variable fragment antibody (scFv) against Citreoviridin toxin. Journal of Agricultural and Food Chemistry, 2016, 64: 7640-7648.
29) Xinyi Nie, Song Yu, MengguangQiu, Xiuna Wang, Yu Wang, Youhuang Bai, Feng Zhang, Shihua Wang*. Aspergillus flavus SUMO Contributes to the Fungal Virulence and Toxin Attributes. Journal of Agricultural and Food Chemistry, 2016, 64: 6772-6782.
30) Weijuan Yang, Jinghua Chen, Guonan Chen, Shihua Wang*, Fengfu Fu*. The early diagnosis and fast detection of blast fungus, Magnaporthegrisea, in rice plant by using its chitinase as biochemical marker and a rice cDNA encoding mannose-binding lectin as recognition probe. Biosensors and Bioelectronics, 2013, 41: 820-826.
31) Rongzhi Wang, Shuangshuang Xiang, Yonghui Zhang, Qiuyu Chen, Yanfang Zhong, Shihua Wang*. Development of functional antibody using green fluorescence protein (GFP) frame as template. Applied and Environmental Microbiology, 2014, 80 (14) : 4126-4137.
32) Rongzhi Wang, Sui Fang, Dinglong Wu, JunweiLian, Jue Fan, Yanfeng Zhang, Shihua Wang*, Wenxiong Lin*. Screening of a ScFv Antibody that can neutralize effectively the cytotoxicity of Vibrio parahaemolytucsTLH. Applied and Environmental Microbiology, 2012, 78 (14): 4967-4975.
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